Transcriptional regulation in cardiac muscle. Coordinate expression of Id with a neonatal phenotype during development and following a hypertrophic stimulus in adult rat ventricular myocytes in vitro.

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Article

Transcriptional regulation in cardiac muscle. Coordinate expression of Id with a neonatal phenotype during development and following a hypertrophic stimulus in adult rat ventricular myocytes in vitro.

The Journal of biological chemistry - 15 Jul 1992

Springhorn J P, Ellingsen O, Berger H J, Kelly R A, Smith T W

Abstract excerpt

The transcriptional regulatory mechanisms in heart muscle that direct cardiac development and allow for a flexible, adaptive response to physiologic stress are not well understood. We demonstrate that a negative regulator of gene transcription termed Id that has been described predominantly in proliferating cell lines and in undifferentiated tissue during growth, is expressed in freshly isolated terminally...

Topics

Aging
Amino Acid Sequence
Animals
Animals, Newborn
Base Sequence
Cells, Cultured
DNA
DNA Probes
DNA-Binding Proteins
Genes, Regulator
Heart

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heart Ventricles

Inhibitor of Differentiation Protein 1

Male

Molecular Sequence Data

Phenotype

RNA

Rats

Source

Open in PubMed

Identifiers

PMID: 1378442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1378442-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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