Article
[Plasticity of myocardial phenotype during cardiac hypertrophy and failure].
Bulletin de l'Academie nationale de medecine - 1 Jun 1993
Mercadier J J, Lompre A M, Swynghedauw B, Schwartz K
Abstract excerpt
Cardiac hypertrophy and failure frequently cause complications in some cardiovascular diseases. Both conditions are associated with important modifications of the heart's contractile and endocrine functions, induced by various changes in gene expression, which in turn are attributable to chronic hemodynamic overload. Differential expression of the myosin heavy chain family leads to a disproportionate accumulation...
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