Two different molecules, NGF and free-HCNP, stimulate cholinergic activity in septal nuclei in vitro in a different manner.

doi:10.1016/0165-3806(94)90043-4

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Article

Two different molecules, NGF and free-HCNP, stimulate cholinergic activity in septal nuclei in vitro in a different manner.

Brain research. Developmental brain research - 13 May 1994

Ojika K, Mitake S, Kamiya T, Kosuge N, Taiji M

Abstract excerpt

Hippocampal cholinergic neurostimulating peptide (HCNP), a novel peptide purified from 10- to 12-day-old rat hippocampus, specifically enhances acetylcholine (AcCho) synthesis in medial septal nuclei in vitro, synthetic de-acetylated HCNP (free-HCNP) elicits more potent enhancement than HCNP. Nerve growth factor (NGF), a neurotrophic substance found in the hippocampus, enhances the cholinergic activity of medial...

Topics

Acetylcholine
Amino Acid Sequence
Animals
Cells, Cultured
Choline
Choline O-Acetyltransferase
Corpus Striatum
Hippocampus
Kinetics
Molecular Sequence Data
Nerve Growth Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nerve Tissue Proteins

Neurons

Neuropeptides

Parasympathetic Nervous System

Phenotype

Rats

Rats, Wistar

Source

Open in PubMed

Identifiers

PMID: 8070052
DOI: 10.1016/0165-3806(94)90043-4

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8070052-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Two different molecules, NGF and free-HCNP, stimulate cholinergic activity in septal nuclei in vitro in a different manner.PMID 8070052Read ↗

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