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Article

Evolution of the interleukin-1 gene family in mammals.

Journal of molecular evolution - 1 Jul 1994

Hughes A L

Abstract excerpt

The phylogeny of interleukin-1 family genes shows that human interleukin-1 alpha (IL-1 alpha) is more closely related to IL-1 alpha of the bovine than to IL-1 alpha of the mouse, whereas human interleukin-1 beta (IL-1 beta) is more closely related to IL-1 beta of the mouse than to IL-1 beta of the bovine. The IL-1 receptor antagonist (IL-1ra) shows homology to the C-terminal region of both IL-1 alpha and IL-1...

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PMID: 8064874
DOI: 10.1007/BF00178244

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