Distinctive structure and function of human apolipoprotein variant ApoA-IV-2.

Article

Distinctive structure and function of human apolipoprotein variant ApoA-IV-2.

The Journal of biological chemistry - 25 Oct 1990

Weinberg R B, Jordan M K, Steinmetz A

Abstract excerpt

We have investigated the molecular structure, phospholipid binding, and lecithin-cholesterol acyltransferase catalytic activity of pure apoA-IV-2, a basic variant isoform of apoA-IV which is inherited as a classical Mendelian allele with a gene frequency of 0.09. Circular dichroism spectroscopy e...

Topics

Alleles
Apolipoproteins A
Circular Dichroism
Enzyme Activation
Humans
In Vitro Techniques
Molecular Structure
Phosphatidylcholine-Sterol O-Acyltransferase
Phospholipids
Protein Conformation
Protein Denaturation
Spectrometry, Fluorescence

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