Plasmid-mediated induction of recombination in yeast.

doi:10.1093/genetics/137.1.41

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Article

Plasmid-mediated induction of recombination in yeast.

Genetics - 1 May 1994

Silberman R, Kupiec M

Abstract excerpt

Diploid yeast cells heteroallelic at the HIS3 locus were transformed with a minichromosome (centromeric plasmid) carrying homology to the HIS3 region and containing the same two mutations as were present in the chromosomes. When a double-strand break (DSB) was introduced in the region of homology...

Topics

DNA Damage
Diploidy
Mutation
Plasmids
Recombination, Genetic
Restriction Mapping
Saccharomyces cerevisiae
Transformation, Genetic

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