Article
The relationship between [Ca2+]i and cell death using an in vivo model: a study using the ced-1 mutant strain of C. elegans.
Toxicologic pathology - 1 Jan 2000
Jain P T, Chang S H, Gutry P P, Berezesky I K, Trump B F
Abstract excerpt
The ced-1 mutant of the free-living nematode, Caenorhabitis elegans, was used to study cell injury and cell death in relation to changes in intracellular ionized calcium ([Ca2+]i). This animal, which is being genetically characterized, may prove to be extremely useful for certain toxicologic studies because of its small size, optical transparency, rapid generation time, and the morphologic and genetic data...
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