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Article

High-resolution loading tests in the study of genetic heterogeneity in gangliosidosis fibroblasts.

Journal of inherited metabolic disease - 1 Jan 1994

Akhunov V S, Mirenburg T V, Krasnopolskaya X D

Abstract excerpt

GM1- and GM2-gangliosides were isolated from brain and radiolabelled. The labelled moieties were localized by hydrolysis with lysosomal enzymes, followed by thin-layer chromatography of the products. High-resolution loading tests with labelled gangliosides were developed and found to differentiate infantile and juvenile forms of GM1- and GM2-gangliosidoses as well as the identification of B, O and AB types of...

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Identifiers

PMID: 8051915
DOI: 10.1007/BF00735405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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