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Article

Classification of disorders of GM2 ganglioside hydrolysis using 3H-GM2 as substrate.

Biochimica et biophysica acta - 2 Mar 1994

Novak A, Callahan J W, Lowden J A

Abstract excerpt

Rates of GM2 ganglioside hydrolysis by fibroblasts from normal controls and patients with GM2 gangliosidosis were measured in situ, with cells growing in tissue culture by assaying the decrease in cell-incorporated 3H-GM2 over time, and in vitro by assaying the rate of 3H-GM2 hydrolysis using fibroblast extracts in the presence of no additives, sodium taurocholate, and GM2 activator protein. In tissue culture,...

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Identifiers

PMID: 8123671
DOI: 10.1016/0304-4165(94)90118-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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