Article
Vibrio cholerae fur mutations associated with loss of repressor activity: implications for the structural-functional relationships of fur.
Journal of bacteriology - 1 Aug 1994
Lam M S, Litwin C M, Carroll P A, Calderwood S B
Abstract excerpt
We used the Vibrio cholerae Fur protein as a model of iron-sensitive repressor proteins in gram-negative bacteria. Utilizing manganese mutagenesis, we isolated twelve independent mutations in V. cholerae fur that resulted in partial or complete loss of Fur repressor function. The mutant fur genes...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- DNA Primers
- DNA, Bacterial
- DNA-Binding Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Iron
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Repressor Proteins
- Structure-Activity Relationship
- Vibrio cholerae