Article
Molecular analysis of the fur (ferric uptake regulator) gene of a pathogenic Edwardsiella tarda strain.
Journal of microbiology (Seoul, Korea) - 1 Jun 2008
Wang Fang, Cheng Shuang, Sun Kun, Sun Li
Abstract excerpt
The gene encoding the Edwardsiella tarda ferric uptake regulator (Fur(Et)) was cloned from a pathogenic E. tarda strain isolated from diseased fish. Fur(Et) shares 90% overall sequence identity with the Escherichia coli Fur (Fur(Ec)) and was able to complement the mutant phenotype of a fur (Ec)-defective E. coli strain. Mutational analysis indicated that C92S and C95S mutations inactivated Fur(Et) whereas E112K...
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