Article
Multiple phenotypes resulting from a mutagenesis screen for pharynx muscle mutations in Caenorhabditis elegans.
PloS one - 1 Jan 2011
Ferrier Andrew, Charron Alexandra, Sadozai Yama, Switaj Lynn, Szutenbach Anneliese, Smith Pliny A
Abstract excerpt
We describe a novel screen to isolate pharyngeal cell morphology mutants in Caenorhabditis elegans using myo-2::GFP to rapidly identify abnormally shaped pharynxes in EMS (Ethyl Methanesulfonate) mutagenized worms. We observed over 83 C. elegans lines with distinctive pharyngeal phenotypes in worms surviving to the L1 larval stage, with phenotypes ranging from short pharynx, unattached pharynx, missing cells,...
Topics
- Animals
- Caenorhabditis elegans
- Feeding Behavior
- Mutagenesis
- Pharynx
- Phenotype
- Polymorphism, Single Nucleotide