[Allelic variants of genes: angiotensin I-converting enzyme (ACE), angiotensin-II type 1 receptor (AT1R), methylenetetrahydrofolate reductase and left ventricular mass in patients with myocardial infarction].

Abstract excerpt

BACKGROUND: Ischemic heart disease has a complex etiology apparently involving gene polymorphisms in the renin-angiotensin system. I/D ACE, A11166C AT1R and C677T MTHFR polymorphisms seem to be associated with a higher risk of myocardial infarction. The aim of this study was to establish the distribution of ACE, AT1R and MTHFR genotypes, and search for correlations with left ventricular anatomic measurements in...

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