Article
Association study of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with myocardial infarction.
Experimental & molecular medicine - 30 Apr 2004
Iqbal M Perwaiz, Mahmood Saeed, Mehboobali Naseema, Ishaq Mohammad, Fatima Tasnim, Parveen Saddiqa, Frossard Philippe
Abstract excerpt
The angiotensin converting enzyme (ACE) is a strong candidate gene for myocardial infarction (MI). Insertion-deletion dimorphism in intron 16 of this gene has been inconclusively found to be associated with it. Several new polymorphisms in the ACE gene have been identified and among these, a dimorphism in exon 17, ACE G2350A, has a significant effect on plasma ACE concentrations. To assess the value of genotyping...
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