Article
The angiotensin I-converting enzyme gene polymorphism: implication in hypertension and myocardial infarction.
Current opinion in nephrology and hypertension - 1 Jan 1994
Soubrier F, Cambien F
Abstract excerpt
The angiotensin I-converting enzyme gene is one of the major genes of the renin-angiotensin and kallikrein-kinin systems and is a candidate gene for several cardiovascular diseases for which a genetic predisposition has been established. Based on analysis of the level of the enzyme in plasma, a genetic polymorphism of its expression has been well characterized. Use of a DNA marker on the angiotensin I-converting...
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