Mutations in the coding region of c-myc occur frequently in acquired immunodeficiency syndrome-associated lymphomas.

Article

Mutations in the coding region of c-myc occur frequently in acquired immunodeficiency syndrome-associated lymphomas.

Blood - 1 Aug 1994

Bhatia K, Spangler G, Gaidano G, Hamdy N, Dalla-Favera R, Magrath I

Abstract excerpt

We have analyzed 30 cases of high- and intermediate-grade acquired immunodeficiency syndrome-associated non-Hodgkin's lymphoma (AIDS-NHL) for mutations in the c-myc coding region. In addition, in these same tumors, we have sought the presence of mutations in a regulatory region within the first c...

Topics

Base Sequence
DNA Primers
Exons
Genes, myc
Humans
Lymphoma, AIDS-Related
Molecular Sequence Data
Mutation
Regulatory Sequences, Nucleic Acid

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.