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Article

Evidence for phenotypic bistability resulting from transcriptional interference of bvgAS in Bordetella bronchiseptica.

Molecular microbiology - 1 Nov 2013

Mason Eliza, Henderson Michael W, Scheller Erich V, Byrd Matthew S, Cotter Peggy A

Abstract excerpt

Bordetella species cause respiratory infections in mammals. Their master regulatory system BvgAS controls expression of at least three distinct phenotypic phases in response to environmental cues. The Bvg⁺ phase is necessary and sufficient for respiratory infection while the Bvg⁻ phase is required for survival ex vivo. We obtained large colony variants (LCVs) from the lungs of mice infected with B. bronchiseptica...

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Identifiers

PMID: 24007341
DOI: 10.1111/mmi.12394
PMCID: PMC4216693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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