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Article

Global DNA hypomethylation increases progressively in cervical dysplasia and carcinoma

1 Aug 1994

Abstract excerpt

BACKGROUND: Global DNA hypomethylation has been observed in some human neoplasms and has been implicated as an important factor in carcinogenesis. The current study was designed to assess whether DNA hypomethylation occurs in cervical dysplasia and cancer, and to determine the relationship between the degree of DNA hypomethylation and the grade of neoplasia. METHODS: Cervical biopsy specimens were obtained from...

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Share to Cervical Cancer and HPV Research
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PMID: 8039116
DOI: 10.1002/1097-0142(19940801)74:3<893::aid-cncr2820740316>3.0.co;2-b

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