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Article

Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis

16 Jan 2013

Abstract excerpt

Deregulated expression of microRNAs (miRNAs) is common and biologically relevant in cervical carcinogenesis and appears only partly related to chromosomal changes. We recently identified 32 miRNAs showing decreased expression in high-grade cervical intraepithelial neoplasia (CIN) and carcinomas not associated with a chromosomal loss, 6 of which were located within a CpG island. This study aimed to investigate to...

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PMID: 23324622
DOI: 10.4161/epi.23605

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