Article
[The use of verapamil in tests for determining the drug resistance of leukemic blasts].
Gematologiia i transfuziologiia - 1 May 1993
Mukhammed A, Turkina A G, Al'pidovskiĭ V K, Sidorova T A, Golenko O D, Gerasimova G K
Abstract excerpt
To determine prognostically unfavourable groups of acute leukemia patients, the authors studied the in vitro accumulation of 3H-vincristine (Vcr) and adriamycin (ADR) as well as inclusion of 3H-cytosar (Ara-C) into marrow blast DNA from patients showing different effects of treatment. It was foun...
Topics
- Adolescent
- Adult
- Aged
- Drug Resistance
- Drug Screening Assays, Antitumor
- Humans
- Leukemia, Myeloid, Acute
- Middle Aged
- Phenotype
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Tritium
- Tumor Cells, Cultured
- Verapamil
