Article
Urate oxidase is imported into peroxisomes recognizing the C-terminal SKL motif of proteins.
European journal of biochemistry - 1 Jul 1994
Miura S, Oda T, Funai T, Ito M, Okada Y, Ichiyama A
Abstract excerpt
Rat liver urate oxidase synthesized from cDNA through coupled transcription and translation was incubated at 26 degrees C for 60 min with purified peroxisomes from rat liver. Urate oxidase was efficiently imported into the peroxisomes, as determined by resistance to externally added proteinase K....
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Transport
- Humans
- Liver
- Microbodies
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Oligopeptides
- Rats
- Temperature
- Time Factors
- Urate Oxidase