Article
Import of chemically synthesized signal peptides into rat liver mitochondria.
The Journal of biological chemistry - 25 Aug 1990
Pak Y K, Weiner H
Abstract excerpt
The signal peptides of pre-aldehyde dehydrogenase (22-mer) and pre-ornithine transcarbamylase (27-mer) were chemically synthesized and their imports into rat liver mitochondria were studied. Both signal peptides were imported rapidly (within 2 min) in the absence of a membrane potential, exogenous ATP, or rabbit reticulocyte lysate. Signal peptides also were imported into mitochondria treated with a low...
Topics
- Aldehyde Dehydrogenase
- Amino Acid Sequence
- Animals
- Circular Dichroism
- Kinetics
- Male
- Mitochondria, Liver
- Molecular Sequence Data
- Mutation
- Ornithine Decarboxylase
- Protein Binding
- Protein Biosynthesis