Changes in substrate specificity of the recombinant form of phenol sulfotransferase IV (tyrosine-ester sulfotransferase).

doi:10.1016/0009-2797(94)90050-7

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Article

Changes in substrate specificity of the recombinant form of phenol sulfotransferase IV (tyrosine-ester sulfotransferase).

Chemico-biological interactions - 1 Jun 1994

Guo W X, Yang Y S, Chen X, McPhie P, Jakoby W B

Abstract excerpt

The over-expression of mammalian enzymes in bacterial systems by means of recombinant DNA technology has provided the enzymologist with a supply of catalyst sufficiently abundant to identify suboptimal substrates. Such large quantities are particularly useful when working with the enzymes of deto...

Topics

Animals
Arylsulfotransferase
Escherichia coli
Hydrogen-Ion Concentration
Kinetics
Liver
Mutation
Rats
Recombinant Proteins
Substrate Specificity

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