Article
Functional consequences of mutations in HIV-1 Gag p55 selected by CTL pressure.
Virology - 15 Aug 1994
Zhang W H, Hockley D J, Nermut M V, Jones I M
Abstract excerpt
Amino acid changes in the CA domain of the p55 Gag protein of HIV-1 have been observed during the course of an infection that appear to correlate with escape from cytotoxic T cell surveillance (Phillips et al., Nature 354, 453-459, 1991). A corollary of this observation is that all such changes should be functionally silent but, as the changes were observed in populations of virus, this has not been formally...
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