Functional consequences of mutations in HIV-1 Gag p55 selected by CTL pressure.

doi:10.1006/viro.1994.1459

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Article

Functional consequences of mutations in HIV-1 Gag p55 selected by CTL pressure.

Virology - 15 Aug 1994

Zhang W H, Hockley D J, Nermut M V, Jones I M

Abstract excerpt

Amino acid changes in the CA domain of the p55 Gag protein of HIV-1 have been observed during the course of an infection that appear to correlate with escape from cytotoxic T cell surveillance (Phillips et al., Nature 354, 453-459, 1991). A corollary of this observation is that all such changes s...

Topics

Amino Acid Sequence
Animals
Baculoviridae
Base Sequence
Gene Products, gag
Genes, gag
HIV-1
Molecular Sequence Data
Moths
Mutation
Protein Precursors
Recombinant Proteins
T-Lymphocytes, Cytotoxic
Virion

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