Minisatellite isoalleles can be distinguished by single-stranded conformational polymorphism analysis in agarose gels.

doi:10.1093/nar/22.11.2155

Back to search

Article

Minisatellite isoalleles can be distinguished by single-stranded conformational polymorphism analysis in agarose gels.

Nucleic acids research - 11 Jun 1994

Monckton D G, Jeffreys A J

Abstract excerpt

Minisatellite isoallelism, i.e. the occurrence of minisatellite alleles with different internal sequence composition but indistinguishable length, is a common limitation of minisatellite allele length analysis. Internal sequence variation can be used to distinguish such isoalleles, provided that...

Topics

Alleles
Blotting, Southern
DNA, Satellite
DNA, Single-Stranded
Electrophoresis, Agar Gel
Polymerase Chain Reaction
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.