Distinguishing minisatellite mutation from non-paternity by MVR-PCR.

doi:10.1016/s0379-0738(00)00263-2

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Article

Distinguishing minisatellite mutation from non-paternity by MVR-PCR.

Forensic science international - 11 Sept 2000

Tamaki K, Brenner C H, Jeffreys A J

Abstract excerpt

Minisatellite variant repeat (MVR) mapping using the polymerase chain reaction (PCR) was devised to map the interspersion pattern of subtle variant repeats along minisatellite tandem arrays. MVR-PCR has revealed enormous diversity of allele structures at several loci, far more than can be resolved by allele length analysis. We have reported the application of MVR-PCR at minisatellite MS32 (D1S8) and MS31A (D7S21)...

Topics

Bias
Complementarity Determining Regions
DNA Fingerprinting
Databases, Factual
Genetic Variation
Germ-Line Mutation
Humans
Minisatellite Repeats
Models, Genetic
Paternity
Pedigree
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 10978602
DOI: 10.1016/s0379-0738(00)00263-2

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