Minisatellite "isoallele" discrimination in pseudohomozygotes by single molecule PCR and variant repeat mapping.

doi:10.1016/0888-7543(91)90158-b

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Article

Minisatellite "isoallele" discrimination in pseudohomozygotes by single molecule PCR and variant repeat mapping.

Genomics - 1 Oct 1991

Monckton D G, Jeffreys A J

Abstract excerpt

The D1S8 hypervariable minisatellite MS32 has a heterozygosity of 97.5% based on detectable differences in allele length using standard Southern blot analysis. It has previously been shown that the basic repeat unit is in itself variable and that this may be used to map the internal structure of...

Topics

Alleles
Base Sequence
DNA, Satellite
Heterozygote
Homozygote
Humans
Molecular Sequence Data
Multigene Family
Polymerase Chain Reaction
Restriction Mapping
Sequence Homology, Nucleic Acid

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