Article
Minisatellite "isoallele" discrimination in pseudohomozygotes by single molecule PCR and variant repeat mapping.
Genomics - 1 Oct 1991
Monckton D G, Jeffreys A J
Abstract excerpt
The D1S8 hypervariable minisatellite MS32 has a heterozygosity of 97.5% based on detectable differences in allele length using standard Southern blot analysis. It has previously been shown that the basic repeat unit is in itself variable and that this may be used to map the internal structure of an allele. This method has already been used to establish that alleles of the same length may have differing internal...
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