HLA class II and class I polymorphism in Venezuelan patients with myasthenia gravis.

doi:10.1016/j.humimm.2003.10.003

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Article

HLA class II and class I polymorphism in Venezuelan patients with myasthenia gravis.

Human immunology - 1 Jan 2004

Fernández-Mestre Mercedes T, Vargas Vivian, Montagnani Silvia, Cotúa Maritza, Ogando Violeta, Layrisse Zulay

Abstract excerpt

Oligotyping performed among ethnically mixed Venezuelan patients with myasthenia gravis (MG) and controls has revealed positive associations of HLA class I A*31, B*08, B*39, B*40, C*15, C*17, and class II DRB1*09 and negative associations of DQB1*06 and DQA1*02 with the disease. Sequential removal of human leukocyte antigen B (HLA-B) alleles when relative predispositional effects (RPEs) were looked for...

Topics

Adult
Alleles
Autoimmune Diseases
Ethnicity
Female
Gene Frequency
Genes, MHC Class I
Genes, MHC Class II
Genetic Predisposition to Disease
Humans
Hyperplasia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Myasthenia Gravis

Phenotype

Polymorphism, Genetic

Thymoma

Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 14700596
DOI: 10.1016/j.humimm.2003.10.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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