Frequent p53 gene involvement in splenic B-cell leukemia/lymphomas of possible marginal zone origin.

Article

Frequent p53 gene involvement in splenic B-cell leukemia/lymphomas of possible marginal zone origin.

Blood - 1 Jul 1994

Baldini L, Fracchiolla N S, Cro L M, Trecca D, Romitti L, Polli E, Maiolo A T, Neri A

Abstract excerpt

A phenotypic and molecular evaluation was made of 15 patients with mature B-cell leukemia/lymphoma showing exclusive spleen and bone marrow involvement. According to French-American-British criteria, these cases could not be classified as classical B-cell chronic lymphocytic leukemia, hairy cell...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Chromosome Aberrations
Female
Genes, p53
Humans
Leukemia, B-Cell
Lymphoma, B-Cell
Male
Middle Aged
Molecular Sequence Data
Mutation
Splenic Neoplasms

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