Article
Analysis of the frequency of microsatellite instability and p53 gene mutation in splenic marginal zone and MALT lymphomas.
Molecular pathology : MP - 1 Oct 1998
Sol Mateo M, Mollejo M, Villuendas R, Algara P, Sánchez-Beato M, Martinez-Delgado B, Martínez P, Piris M A
Abstract excerpt
AIMS: Studies of the genetic characteristics of splenic marginal zone lymphoma (SMZL) have failed to identify genetic changes specific to this tumour. Microsatellite instability is a type of genomic instability associated with different types of human cancer. Although microsatellite instability is rare in B cell non-Hodgkin's lymphomas, it has been found in some specific subsets, such as marginal zone lymphomas...
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