Muller's ratchet under epistatic selection.

doi:10.1093/genetics/136.4.1469

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Article

Muller's ratchet under epistatic selection.

Genetics - 1 Apr 1994

Kondrashov A S

Abstract excerpt

In a finite asexual population mean fitness may decrease by a process known as Muller's ratchet, which proceeds if all individuals with the minimum number of deleterious alleles are randomly lost. If these alleles have independent effects on fitness, previous analysis suggested that the rate of t...

Topics

Computer Simulation
Genetics, Population
Models, Genetic
Mutation
Selection, Genetic

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