Article
Beneficial mutation selection balance and the effect of linkage on positive selection.
Genetics - 1 Jul 2007
Desai Michael M, Fisher Daniel S
Abstract excerpt
When beneficial mutations are rare, they accumulate by a series of selective sweeps. But when they are common, many beneficial mutations will occur before any can fix, so there will be many different mutant lineages in the population concurrently. In an asexual population, these different mutant lineages interfere and not all can fix simultaneously. In addition, further beneficial mutations can accumulate in...
Topics
- Genetic Linkage
- Genetic Variation
- Genetics, Population
- Models, Genetic
- Mutation
- Reproduction
- Reproduction, Asexual
- Selection, Genetic
