Article
High resolution of quantitative traits into multiple loci via interval mapping.
Genetics - 1 Apr 1994
Jansen R C, Stam P
Abstract excerpt
A very general method is described for multiple linear regression of a quantitative phenotype on genotype [putative quantitative trait loci (QTLs) and markers] in segregating generations obtained from line crosses. The method exploits two features, (a) the use of additional parental and F1 data, which fixes the joint QTL effects and the environmental error, and (b) the use of markers as cofactors, which reduces...
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