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Article

The role of macronuclear DNA sequences in the permanent rescue of a non-mendelian mutation in Paramecium tetraurelia.

Genetics - 1 Apr 1994

You Y, Scott J, Forney J

Abstract excerpt

The paramecium tetraurelia mutant called d48 has a complete copy of the A surface protein gene in its micronuclei, but lacks the A gene in the macronucleus. Previous experiments have shown that microinjection of a plasmid containing the entire A gene or a large portion of the gene into the macronucleus of d48 rescued the cell line after formation of a new macronucleus (autogamy). Here we show that several...

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Identifiers

PMID: 8013908
DOI: 10.1093/genetics/136.4.1319
PMCID: PMC1205912

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