Induction of specific macronuclear developmental mutations by microinjection of a cloned telomeric gene in Paramecium primaurelia.

doi:10.1101/gad.6.2.211

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Article

Induction of specific macronuclear developmental mutations by microinjection of a cloned telomeric gene in Paramecium primaurelia.

Genes & development - 1 Feb 1992

Meyer E

Abstract excerpt

In Paramecium, the differentiation of a highly polyploid macronucleus from a diploid nucleus is accompanied by an extensive reorganization of the genome, involving reduction in chromosome size and formation of new telomeres at heterogeneous, but reproducible, positions. The results presented here...

Topics

Animals
Antigens, Protozoan
Blotting, Southern
Cell Nucleus
Microinjections
Mutation
Paramecium
Recombination, Genetic
Telomere
Transformation, Genetic

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