Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting.

doi:10.1038/ng0394-310

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Article

Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting.

Nature genetics - 1 Mar 1994

Giddings S J, King C D, Harman K W, Flood J F, Carnaghi L R

Abstract excerpt

Genomic imprinting, gene inactivation during gametogenesis, causes maternal and paternal alleles of some genes to function unequally. We examined the possibility of imprinting in insulin genes because the human insulin gene (ins) and its mouse homologue (ins2) are adjacent to the known imprinted...

Topics

Alleles
Animals
Base Sequence
Crosses, Genetic
DNA Primers
DNA, Complementary
Female
Gene Expression
Humans
Insulin
Insulin-Like Growth Factor II
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Molecular Sequence Data
Muridae
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8012396
DOI: 10.1038/ng0394-310

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8012396-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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