Article
Analysis of the envelope region of the highly divergent HIV-2ALT isolate extends the known range of variability within the primate immunodeficiency viruses.
AIDS research and human retroviruses - 1 Sept 1992
Kreutz R, Dietrich U, Kühnel H, Nieselt-Struwe K, Eigen M, Rübsamen-Waigmann H
Abstract excerpt
HIV-2ALT is a highly divergent HIV-2-related isolate that is genetically equidistant to the prototypic HIV-2 strains, defined by HIV-2ROD, and to the simian immunodeficiency viruses SIVmac and SIVsm. We have now cloned and sequenced the envelope region of HIV-2ALT, thus completing the analysis of the whole viral genome. The sequences of env and nef and of the second exons of tat and rev were compared with those...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA, Viral
- Genetic Variation
- HIV-2
- Humans
- Molecular Sequence Data
- Open Reading Frames
- Phylogeny