Article
Tropism, coreceptor use, and phylogenetic analysis of both the V3 loop and the protease gene of three novel HIV-1 group O isolates.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 15 Aug 1998
Vallejo A, Heredia A, Mas A, Lee S F, Epstein J S, Soriano V, Hewlett I K
Abstract excerpt
HIV-1 has been subdivided into two groups, M and O, based on phylogenetic analysis. To better understand the pathogenesis of group O viruses, we studied biologic and genetic characteristics of two primary isolates from Spain, ES1158.1 and ES1159.1, and one from the United States, MD.1. After vira...
Topics
- Amino Acid Sequence
- Cell Line
- Cells, Cultured
- Coculture Techniques
- Consensus Sequence
- HIV Envelope Protein gp120
- HIV Protease
- HIV-1
- Humans
- Leukocytes, Mononuclear
- Macrophages
- Molecular Sequence Data
- Monocytes