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Article

Tropism, coreceptor use, and phylogenetic analysis of both the V3 loop and the protease gene of three novel HIV-1 group O isolates.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 15 Aug 1998

Vallejo A, Heredia A, Mas A, Lee S F, Epstein J S, Soriano V, Hewlett I K

Abstract excerpt

HIV-1 has been subdivided into two groups, M and O, based on phylogenetic analysis. To better understand the pathogenesis of group O viruses, we studied biologic and genetic characteristics of two primary isolates from Spain, ES1158.1 and ES1159.1, and one from the United States, MD.1. After viral isolation, we studied the replication kinetics in peripheral blood mononuclear cells (PBMCs) and macrophages, as well...

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Identifiers

PMID: 9715837
DOI: 10.1097/00042560-199808150-00002

Genes

MVP
CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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