Article
The SPI-1 gene of rabbitpox virus determines host range and is required for hemorrhagic pock formation.
Virology - 1 Jul 1994
Ali A N, Turner P C, Brooks M A, Moyer R W
Abstract excerpt
Wild-type rabbitpox virus (RPV) and cowpox virus (CPV) produce red hemorrhagic lesions or pocks upon infection of the chicken chorioallantoic membrane (CAM) of 11-day-old embryonated chicken eggs. However, white, nonhemorrhagic pock variants arise spontaneously within wild-type (wt) populations of either virus at a frequency of about 1%, reflective of complex deletions/rearrangements in the termini of the viral...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Chick Embryo
- Cowpox virus
- DNA, Viral
- Genes, Viral
- Humans
- Intercellular Signaling Peptides and Proteins
- Intracellular Signaling Peptides and Proteins
