Leishmania major HEXBP deletion mutants generated by double targeted gene replacement.

doi:10.1016/0166-6851(94)90059-0

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Article

Leishmania major HEXBP deletion mutants generated by double targeted gene replacement.

Molecular and biochemical parasitology - 1 Feb 1994

Webb J R, McMaster W R

Abstract excerpt

The Leishmania major single-stranded DNA binding protein HEXBP contains nine 'CCHC' zinc finger motifs and binds to oligodeoxynucleotides derived from the antisense strand of the GP63 gene 5' flanking region in gel mobility shift assays and UV-crosslinking assays. In the present study a HEXBP-def...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
DNA-Binding Proteins
Drug Resistance
Genes, Protozoan
Genetic Markers
Gentamicins
Hygromycin B
Leishmania major
Metalloendopeptidases
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Multigene Family
Mutagenesis
Protozoan Proteins

Source

Open in PubMed

Identifiers

PMID: 8008021
DOI: 10.1016/0166-6851(94)90059-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8008021-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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