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Article

Inducible knockdown of Plasmodium gene expression using the glmS ribozyme.

PloS one - 1 Jan 2013

Prommana Parichat, Uthaipibull Chairat, Wongsombat Chayaphat, Kamchonwongpaisan Sumalee, Yuthavong Yongyuth, Knuepfer Ellen, Holder Anthony A, Shaw Philip J

Abstract excerpt

Conventional reverse genetic approaches for study of Plasmodium malaria parasite gene function are limited, or not applicable. Hence, new inducible systems are needed. Here we describe a method to control P. falciparum gene expression in which target genes bearing a glmS ribozyme in the 3' untranslated region are efficiently knocked down in transgenic P. falciparum parasites in response to glucosamine inducer....

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Identifiers

PMID: 24023691
DOI: 10.1371/journal.pone.0073783
PMCID: PMC3758297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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