Article
Cosegregation of codon 807 mutation of the canine rod cGMP phosphodiesterase beta gene and rcd1.
Investigative ophthalmology & visual science - 1 Dec 1994
Ray K, Baldwin V J, Acland G M, Blanton S H, Aguirre G D
Abstract excerpt
PURPOSE: To determine if a previously reported nonsense mutation (G to A transition at nucleotide position 2420) in the canine rod cyclic GMP (cGMP) phosphodiesterase beta (PDEB) subunit gene cosegregates with the rod-cone dysplasia 1 disease allele (rcd1) in the rcd1-dog reference colony; to establish the prevalence of this mutation among rcd1-affected Irish setters in the United States; and to screen for this...
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