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Article

Genetic screening for PRA-associated mutations in multiple dog breeds shows that PRA is heterogeneous within and between breeds.

Veterinary ophthalmology - 1 Mar 2014

Downs Louise M, Hitti Rebekkah, Pregnolato Silvia, Mellersh Cathryn S

Abstract excerpt

OBJECTIVE: To assess the extent of progressive retinal atrophy (PRA) genetic heterogeneity within and between domestic dog breeds. METHODS: DNA from 231 dogs with PRA, representing 36 breeds, was screened for 17 mutations previously associated with PRA in at least one breed of dog. Screening methods included amplified fragment size discrimination using gel electrophoresis or detection of fluorescence, (TaqMan(®)...

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PMID: 24255994
DOI: 10.1111/vop.12122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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