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Article

Krebs cycle function is required for activation of the Spo0A transcription factor in Bacillus subtilis.

Proceedings of the National Academy of Sciences of the United States of America - 28 Mar 1995

Ireton K, Jin S, Grossman A D, Sonenshein A L

Abstract excerpt

Expression of genes early during sporulation in Bacillus subtilis requires the activity of the transcription factor encoded by spo0A. The active, phosphorylated form of Spo0A is produced through the action of a multicomponent pathway, the phosphorelay. A mutant defective in the first three enzymes of the Krebs citric acid cycle was unable to express early sporulation genes, apparently because of a failure to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7708735
DOI: 10.1073/pnas.92.7.2845
PMCID: PMC42315

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Krebs cycle function is required for activation of the Spo0A transcription factor in Bacillus subtilis.PMID 7708735Read ↗

REGULATION OF THE PHOSPHORELAY AND THE INITIATION OF SPORULATION IN <i>BACILLUS SUBTILIS</i>Semantic proximity Read ↗

Signal transduction and sporulation in Bacillus subtilis: autophosphorylation of Spo0A, a sporulation initiation gene product.Semantic proximity Read ↗

Deactivation of the sporulation transcription factor Spo0A by the Spo0E protein phosphatase.Semantic proximity Read ↗

Multiple protein-aspartate phosphatases provide a mechanism for the integration of diverse signals in the control of development in B. subtilis.Semantic proximity Read ↗

Spo0A activates and represses its own synthesis by binding at its dual promoters.Semantic proximity Read ↗

Integration of multiple developmental signals in Bacillus subtilis through the Spo0A transcription factor.Semantic proximity Read ↗

Multiple histidine kinases regulate entry into stationary phase and sporulation in Bacillus subtilis.Semantic proximity Read ↗

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In vivo effects of sporulation kinases on mutant Spo0A proteins in Bacillus subtilis.Semantic proximity Read ↗

Coordination of cell decisions and promotion of phenotypic diversity in B. subtilis via pulsed behavior of the phosphorelay.Semantic proximity Read ↗

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