Article
Krebs cycle function is required for activation of the Spo0A transcription factor in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America - 28 Mar 1995
Ireton K, Jin S, Grossman A D, Sonenshein A L
Abstract excerpt
Expression of genes early during sporulation in Bacillus subtilis requires the activity of the transcription factor encoded by spo0A. The active, phosphorylated form of Spo0A is produced through the action of a multicomponent pathway, the phosphorelay. A mutant defective in the first three enzyme...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Citric Acid Cycle
- Gene Deletion
- Gene Expression
- Genotype
- Glucose
- Kinetics
- Mutagenesis, Insertional
- Phosphorylation
- Promoter Regions, Genetic
- Spores, Bacterial
- Transcription Factors