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Article

Interaction surface of the Spo0A response regulator with the Spo0E phosphatase.

Molecular microbiology - 1 Jun 2002

Stephenson Sophie J, Perego Marta

Abstract excerpt

Spo0A~P is the essential response regulator and transcription factor for sporulation initiation in Bacillus subtilis. The phosphorylation level of Spo0A in the cell is determined by the sensor kinase activity of the phosphorelay, donating phosphoryl groups, and the antagonistic effects of dephosphorylation mediated by the Rap and Spo0E families of phosphatases. In this study, spo0A mutations were generated that...

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Source

Identifiers

PMID: 12067336
DOI: 10.1046/j.1365-2958.2002.02974.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction surface of the Spo0A response regulator with the Spo0E phosphatase.PMID 12067336Read ↗

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In vivo effects of sporulation kinases on mutant Spo0A proteins in Bacillus subtilis.Semantic proximity Read ↗

Lessons and questions from the structure of the Spo0A activation domain.Semantic proximity Read ↗

Bacillus subtilis mutations that alter the pathway of phosphorylation of the anti-anti-sigmaF factor SpoIIAA lead to a Spo- phenotype.Semantic proximity Read ↗

Spo0A activates and represses its own synthesis by binding at its dual promoters.Semantic proximity Read ↗

SpoIIE governs the phosphorylation state of a protein regulating transcription factor sigma F during sporulation in Bacillus subtilis.Semantic proximity Read ↗

Deactivation of the sporulation transcription factor Spo0A by the Spo0E protein phosphatase.Semantic proximity Read ↗

Signal transduction and sporulation in Bacillus subtilis: autophosphorylation of Spo0A, a sporulation initiation gene product.Semantic proximity Read ↗

The Spo0A sof mutations reveal regions of the regulatory domain that interact with a sensor kinase and RNA polymerase.Semantic proximity Read ↗

Dimer form of phosphorylated Spo0A, a transcriptional regulator, stimulates the spo0F transcription at the initiation of sporulation in Bacillus subtilis.Semantic proximity Read ↗

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