Article
Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis.
Structure (London, England : 1993) - 15 Jun 1996
Madhusudan, Zapf J, Whiteley J M, Hoch J A, Xuong N H, Varughese K I
Abstract excerpt
BACKGROUND: Spo0F, a phosphotransferase containing an aspartyl pocket, is involved in the signaling pathway (phosphorelay) controlling sporulation in Bacillus subtilis. It belongs to the superfamily of bacterial response regulatory proteins, which are activated upon phosphorylation of an invariant aspartate residue. This phosphorylation is carried out in a divalent cation dependent reaction catalyzed by cognate...
Topics
- Amino Acid Sequence
- Bacillus subtilis
- Bacterial Proteins
- Binding Sites
- Calcium
- Crystallography, X-Ray
- Gene Expression Regulation, Bacterial
- Models, Molecular
- Molecular Sequence Data
- Mutation