Article
Structure of the human hexokinase II gene.
Biochemical and biophysical research communications - 30 Nov 1994
Malkki M, Laakso M, Deeb S S
Abstract excerpt
Mutations in the gene encoding hexokinase II which catalyzes a key step in glycolysis could contribute to the development of peripheral insulin resistance and lead to non-insulin-dependent diabetes mellitus. As a first step towards screening patients for mutations in this gene, we have determined...
Topics
- Base Sequence
- DNA, Complementary
- Diabetes Mellitus, Type 2
- Exons
- Hexokinase
- Humans
- Introns
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Pseudogenes