Human hexokinase II: localization of the polymorphic gene to chromosome 2.

doi:10.1007/BF00400809

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Article

Human hexokinase II: localization of the polymorphic gene to chromosome 2.

Diabetologia - 1 Dec 1993

Lehto M, Xiang K, Stoffel M, Espinosa R, Groop L C, Le Beau M M, Bell G I

Abstract excerpt

Type 2 (non-insulin-dependent) diabetes mellitus is characterized by decreased levels of glucose 6-phosphate in skeletal muscle. It has been suggested that the lower concentrations of glucose 6-phosphate contribute to the defect in glucose metabolism noted in muscle tissue of subjects with Type 2...

Topics

Alleles
Animals
Asian People
Base Sequence
China
Chromosome Mapping
Chromosomes, Human, Pair 2
Cloning, Molecular
DNA Primers
Female
Gene Frequency
Genomic Library
Hexokinase
Humans
In Situ Hybridization, Fluorescence
Isoenzymes
Lymphocytes
Male

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