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Article

High variability of the gag/pol transframe region among HIV-1 isolates.

Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Feb 1994

Candotti D, Chappey C, Rosenheim M, M'Pelé P, Huraux J M, Agut H

Abstract excerpt

The overlapping region of gag and pol genes of human immunodeficiency virus type 1 (HIV-1) also called transframe region, contains the frameshift locus from gag to pol. This region encodes both the protein p6, the function of which remains unclear, and a putative transframe protein covently linked to the N-terminus of the viral protease within Gag/Pol protein precursor. We have investigated the variability of the...

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PMID: 7994608

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