Article
High variability of the gag/pol transframe region among HIV-1 isolates.
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Feb 1994
Candotti D, Chappey C, Rosenheim M, M'Pelé P, Huraux J M, Agut H
Abstract excerpt
The overlapping region of gag and pol genes of human immunodeficiency virus type 1 (HIV-1) also called transframe region, contains the frameshift locus from gag to pol. This region encodes both the protein p6, the function of which remains unclear, and a putative transframe protein covently linked to the N-terminus of the viral protease within Gag/Pol protein precursor. We have investigated the variability of the...
Topics
- Amino Acid Sequence
- Base Sequence
- Congo
- Gene Products, gag
- Genes, Overlapping
- Genes, gag
- Genes, pol
- Genetic Variation
- HIV-1
- Humans
- Membrane Proteins