Article
Rapid genotyping of the five major platelet alloantigens by reverse dot-blot hybridization.
Blood - 15 Dec 1994
Bray P F, Jin Y, Kickler T
Abstract excerpt
Amino acid substitutions in platelet membrane glycoproteins result in alloantigens. Identifying these polymorphisms is important in alloimmune-mediated platelet disorders. Immunophenotyping platelet antigens can be limited by the unavailability of specific antisera. The goal of this work was to i...
Topics
- Alleles
- Amniocentesis
- Antibodies, Monoclonal
- Antigens, Human Platelet
- Base Sequence
- Enzyme-Linked Immunosorbent Assay
- Female
- Fetal Diseases
- Genotype
- Histocompatibility Testing
- Humans
- Immunity, Maternally-Acquired
- Immunophenotyping
- Isoantibodies
- Male
- Maternal-Fetal Exchange
- Molecular Sequence Data
- Nucleic Acid Hybridization
